Pathogenic Role of mTORC1 and mTORC2 in Pulmonary Hypertension

Concentric lung vascular wall thickening due to enhanced proliferation of pulmonary arterial smooth muscle cells is an important pathological cause for the elevated pulmonary vascular resistance reported in patients with pulmonary arterial hypertension. We identified a differential role of mammalian...

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Dettagli Bibliografici
Pubblicato in:JACC Basic Transl Sci
Autori principali: Tang, Haiyang, Wu, Kang, Wang, Jian, Vinjamuri, Sujana, Gu, Yali, Song, Shanshan, Wang, Ziyi, Zhang, Qian, Balistrieri, Angela, Ayon, Ramon J., Rischard, Franz, Vanderpool, Rebecca, Chen, Jiwang, Zhou, Guofei, Desai, Ankit A., Black, Stephen M., Garcia, Joe G.N., Yuan, Jason X.-J., Makino, Ayako
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2018
Soggetti:
PRECLINICAL RESEARCH
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314964/
https://ncbi.nlm.nih.gov/pubmed/30623134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2018.08.009
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