Pathogenic Role of mTORC1 and mTORC2 in Pulmonary Hypertension

Concentric lung vascular wall thickening due to enhanced proliferation of pulmonary arterial smooth muscle cells is an important pathological cause for the elevated pulmonary vascular resistance reported in patients with pulmonary arterial hypertension. We identified a differential role of mammalian...

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Bibliografski detalji
Izdano u:JACC Basic Transl Sci
Glavni autori: Tang, Haiyang, Wu, Kang, Wang, Jian, Vinjamuri, Sujana, Gu, Yali, Song, Shanshan, Wang, Ziyi, Zhang, Qian, Balistrieri, Angela, Ayon, Ramon J., Rischard, Franz, Vanderpool, Rebecca, Chen, Jiwang, Zhou, Guofei, Desai, Ankit A., Black, Stephen M., Garcia, Joe G.N., Yuan, Jason X.-J., Makino, Ayako
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2018
Teme:
PRECLINICAL RESEARCH
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314964/
https://ncbi.nlm.nih.gov/pubmed/30623134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2018.08.009
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