Both mTORC1 and mTORC2 are involved in the regulation of cell adhesion

mTOR is a central controller for cell growth/proliferation and survival. Recent studies have shown that mTOR also regulates cell adhesion, yet the underlying mechanism is not known. Here we found that inhibition of mTOR by rapamycin reduced the basal or type I insulin-like growth factor (IGF-1)-stim...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chen, Long, Xu, Baoshan, Liu, Lei, Liu, Chunxiao, Luo, Yan, Chen, Xin, Barzegar, Mansoureh, Chung, Jun, Huang, Shile
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466674/
https://ncbi.nlm.nih.gov/pubmed/25762619
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