LPS Induces mTORC1 and mTORC2 Activation During Monocyte Adhesion

Monocyte adhesion is a crucial step in transmigration and can be induced by lipopolysaccharide (LPS). Here, we studied the role of mammalian target of rapamycin (mTOR) complexes, mTORC1 and mTORC2, and PKC in this process. We used THP-1 cells, a human monocytic cell line, to investigate monocyte adh...

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Dades bibliogràfiques
Publicat a:Front Mol Biosci
Autors principals: Ribeiro, Marcelle C., Peruchetti, Diogo B., Silva, Leandro S., Silva-Filho, João L., Souza, Mariana C., Henriques, Maria das Graças, Caruso-Neves, Celso, Pinheiro, Ana Acacia S.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Molecular Biosciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058081/
https://ncbi.nlm.nih.gov/pubmed/30073169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2018.00067
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