Synoviocyte-targeted therapy synergizes with TNF inhibition in arthritis reversal

Fibroblast-like synoviocytes (FLS) are joint-lining cells that promote rheumatoid arthritis (RA) pathology. Current disease-modifying antirheumatic agents (DMARDs) operate through systemic immunosuppression. FLS-targeted approaches could potentially be combined with DMARDs to improve control of RA w...

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Detaylı Bibliyografya
Yayımlandı:Sci Adv
Asıl Yazarlar: Svensson, Mattias N. D., Zoccheddu, Martina, Yang, Shen, Nygaard, Gyrid, Secchi, Christian, Doody, Karen M., Slowikowski, Kamil, Mizoguchi, Fumitaka, Humby, Frances, Hands, Rebecca, Santelli, Eugenio, Sacchetti, Cristiano, Wakabayashi, Kuninobu, Wu, Dennis J., Barback, Christopher, Ai, Rizi, Wang, Wei, Sims, Gary P., Mydel, Piotr, Kasama, Tsuyoshi, Boyle, David L., Galimi, Francesco, Vera, David, Tremblay, Michel L., Raychaudhuri, Soumya, Brenner, Michael B., Firestein, Gary S., Pitzalis, Costantino, Ekwall, Anna-Karin H., Stanford, Stephanie M., Bottini, Nunzio
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Association for the Advancement of Science 2020
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Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7319753/
https://ncbi.nlm.nih.gov/pubmed/32637608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aba4353
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