PTPN14 phosphatase and YAP promote TGFβ signaling in rheumatoid synoviocytes

OBJECTIVE: We aimed to understand the role of the tyrosine phosphatase PTPN14 –which in cancer cells modulates the Hippo pathway by retaining YAP in the cytosol- in fibroblast-like synoviocytes (FLS) from rheumatoid arthritis (RA) patients. METHODS: Gene/protein expression levels were measured by qP...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Ann Rheum Dis
Главные авторы: Bottini, Angel, Wu, Dennis J, Ai, Rizi, Le Roux, Michelle, Bartok, Beatrix, Bombardieri, Michele, Doody, Karen M., Zhang, Vida, Sacchetti, Cristiano, Zoccheddu, Martina, Lonic, Ana, Li, Xiaochun, Boyle, David, Hammaker, Deepa, Meng, Tzu-Ching, Liu, Lin, Corr, Maripat, Stanford, Stephanie M., Lewis, Myles, Wang, Wei, Firestein, Gary S., Khew-Goodall, Yeesim, Pitzalis, Costantino, Bottini, Nunzio
Формат: Artigo
Язык:Inglês
Опубликовано: 2019
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7039277/
https://ncbi.nlm.nih.gov/pubmed/30808624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2018-213799
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы