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Duality of fibroblast-like synoviocytes in RA: passive responders and imprinted aggressors
Rheumatoid arthritis (RA) is characterized by hyperplastic synovial pannus tissue, which mediates destruction of cartilage and bone. Fibroblast-like synoviocytes (FLS) are a key component of this invasive synovium and have a major role in the initiation and perpetuation of destructive joint inflamma...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3970924/ https://ncbi.nlm.nih.gov/pubmed/23147896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrrheum.2012.190 |
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