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Restoring synovial homeostasis in rheumatoid arthritis by targeting fibroblast-like synoviocytes

Rheumatoid arthritis (RA) is a chronic immune-mediated disease that primarily affects the synovium of diarthrodial joints. During the course of RA, the synovium transforms into a hyperplastic invasive tissue that causes destruction of cartilage and bone. Fibroblast-like synoviocytes (FLS), which for...

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Detalhes bibliográficos
Publicado no:Nat Rev Rheumatol
Main Authors: Nygaard, Gyrid, Firestein, Gary S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7987137/
https://ncbi.nlm.nih.gov/pubmed/32393826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41584-020-0413-5
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