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DNA double strand break repair pathway choice in somatic mammalian cells
The major pathways of DNA double strand break (DSB) repair have key roles in suppressing genomic instability. However, if deployed in an inappropriate cellular context, these same repair functions can mediate chromosome rearrangements that underlie various human diseases, ranging from developmental...
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| Pubblicato in: | Nat Rev Mol Cell Biol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7315405/ https://ncbi.nlm.nih.gov/pubmed/31263220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41580-019-0152-0 |
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