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DNA double strand break repair pathway choice in somatic mammalian cells
The major pathways of DNA double strand break (DSB) repair have key roles in suppressing genomic instability. However, if deployed in an inappropriate cellular context, these same repair functions can mediate chromosome rearrangements that underlie various human diseases, ranging from developmental...
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| Published in: | Nat Rev Mol Cell Biol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7315405/ https://ncbi.nlm.nih.gov/pubmed/31263220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41580-019-0152-0 |
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