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DNA double strand break repair pathway choice in somatic mammalian cells

The major pathways of DNA double strand break (DSB) repair have key roles in suppressing genomic instability. However, if deployed in an inappropriate cellular context, these same repair functions can mediate chromosome rearrangements that underlie various human diseases, ranging from developmental...

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Detalhes bibliográficos
Publicado no:Nat Rev Mol Cell Biol
Main Authors: Scully, Ralph, Panday, Arvind, Elango, Rajula, Willis, Nicholas A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7315405/
https://ncbi.nlm.nih.gov/pubmed/31263220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41580-019-0152-0
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