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Mechanisms of double-strand break repair in somatic mammalian cells
DNA chromosomal DSBs (double-strand breaks) are potentially hazardous DNA lesions, and their accurate repair is essential for the successful maintenance and propagation of genetic information. Two major pathways have evolved to repair DSBs: HR (homologous recombination) and NHEJ (non-homologous end-...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2983087/ https://ncbi.nlm.nih.gov/pubmed/19772495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20090942 |
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