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Mechanisms of double-strand-break repair during gene targeting in mammalian cells.

In the present study, the mechanism of double-strand-break (DSB) repair during gene targeting at the chromosomal immunoglobulin mu-locus in a murine hybridoma was examined. The gene-targeting assay utilized specially designed insertion vectors genetically marked in the region of homology to the chro...

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Autors principals: Ng, P, Baker, M D
Format: Artigo
Idioma:Inglês
Publicat: 1999
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1460530/
https://ncbi.nlm.nih.gov/pubmed/10049929
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