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DNA double strand break repair pathway choice in somatic mammalian cells

The major pathways of DNA double strand break (DSB) repair have key roles in suppressing genomic instability. However, if deployed in an inappropriate cellular context, these same repair functions can mediate chromosome rearrangements that underlie various human diseases, ranging from developmental...

詳細記述

保存先:
書誌詳細
出版年:Nat Rev Mol Cell Biol
主要な著者: Scully, Ralph, Panday, Arvind, Elango, Rajula, Willis, Nicholas A.
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7315405/
https://ncbi.nlm.nih.gov/pubmed/31263220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41580-019-0152-0
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