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DNA double strand break repair pathway choice in somatic mammalian cells
The major pathways of DNA double strand break (DSB) repair have key roles in suppressing genomic instability. However, if deployed in an inappropriate cellular context, these same repair functions can mediate chromosome rearrangements that underlie various human diseases, ranging from developmental...
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| Publicado en: | Nat Rev Mol Cell Biol |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7315405/ https://ncbi.nlm.nih.gov/pubmed/31263220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41580-019-0152-0 |
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