Loading...
Repair Pathway Choices and Consequences at the Double-Strand Break
DNA double-strand breaks (DSBs) are cytotoxic lesions that threaten genomic integrity. Failure to repair a DSB has deleterious consequences, including genomic instability and cell death. Indeed, misrepair of DSBs can lead to inappropriate end-joining events, which commonly underlie oncogenic transfo...
Saved in:
| Published in: | Trends Cell Biol |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2015
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4862604/ https://ncbi.nlm.nih.gov/pubmed/26437586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2015.07.009 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|