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Aberrant subchondral osteoblastic metabolism modifies Na(V)1.8 for osteoarthritis
Pain is the most prominent symptom of osteoarthritis (OA) progression. However, the relationship between pain and OA progression remains largely unknown. Here we report osteoblast secret prostaglandin E2 (PGE2) during aberrant subchondral bone remodeling induces pain and OA progression in mice. Spec...
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| 出版年: | eLife |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
eLife Sciences Publications, Ltd
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7308086/ https://ncbi.nlm.nih.gov/pubmed/32441256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.57656 |
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