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Inhibition of cyclooxygenase-2 activity in subchondral bone modifies a subtype of osteoarthritis
Osteoarthritis (OA) causes the destruction of joints. Its pathogenesis is still under investigation, and there is no effective disease-modifying therapy. Here, we report that elevated cyclooxygenase-2 (COX-2) expression in the osteocytes of subchondral bone causes both spontaneous OA and rheumatoid...
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| Vydáno v: | Bone Res |
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| Hlavní autoři: | , , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group UK
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6804921/ https://ncbi.nlm.nih.gov/pubmed/31666999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41413-019-0071-x |
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