Halofuginone Attenuates Osteoarthritis by Rescuing Bone Remodeling in Subchondral Bone Through Oral Gavage

Osteoarthritis (OA) is a common debilitating joint disorder worldwide without effective medical therapy. Articular cartilage and subchondral bone act in concert as a functional unit with the onset of OA. Halofuginone is an analog of the alkaloid febrifugine extracted from the plant Dichroa febrifuga...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Mu, Wenbo, Xu, Boyong, Ma, Hairong, Li, Jiao, Ji, Baochao, Zhang, Zhendong, Amat, Abdusami, Cao, Li
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881118/
https://ncbi.nlm.nih.gov/pubmed/29636687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00269
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