Isoliquiritigenin blunts osteoarthritis by inhibition of bone resorption and angiogenesis in subchondral bone

Isoliquiritigenin (ISL), a natural flavonoid extracted from licorice, has been demonstrated to exert attenuation of osteoclastogenesis and anti-angiogenesis activity in a wide variety of cells. Here, we first evaluated the effects of ISL on pathogenesis of osteoarthritis in a mouse model of OA. The...

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Detalhes bibliográficos
Publicado no:Sci Rep
Principais autores: Ji, Baochao, Zhang, Zhendong, Guo, Wentao, Ma, Hairong, Xu, Boyong, Mu, Wenbo, Amat, Abdusami, Cao, Li
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5788865/
https://ncbi.nlm.nih.gov/pubmed/29379010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19162-y
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