Fluvastatin Induces Apoptosis in Primary and Transformed Mast Cells

Statin drugs are widely employed in the clinic to reduce serum cholesterol. Because of their hydroxymethylglutaryl coenzyme A reductase antagonism, statins also reduce isoprenyl lipids necessary for the membrane anchorage and signaling of small G-proteins in the Ras superfamily. We previously found...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Pharmacol Exp Ther
Hauptverfasser: Paez, Patrick A., Kolawole, Motunrayo, Taruselli, Marcela T., Ajith, Siddarth, Dailey, Jordan M., Kee, Sydney A., Haque, Tamara T., Barnstein, Brian O., McLeod, Jamie Josephine Avila, Caslin, Heather L., Kiwanuka, Kasalina N., Fukuoka, Yoshihiro, Le, Quang T., Schwartz, Lawrence B., Straus, David B., Gewirtz, David A., Martin, Rebecca K., Ryan, John J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Pharmacology and Experimental Therapeutics 2020
Schlagworte:
Inflammation, Immunopharmacology, and Asthma
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7306917/
https://ncbi.nlm.nih.gov/pubmed/32434944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.119.264234
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge