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Fluvastatin Suppresses Mast Cell and Basophil IgE Responses: Genotype-Dependent Effects

Mast cell- and basophil-associated inflammatory diseases are a considerable burden to society. A significant portion of patients have symptoms despite standard-of-care therapy. Statins, used to lower serum cholesterol, have immune modulating activities. We tested the in vitro and in vivo effects of...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Kolawole, Elizabeth Motunrayo, McLeod, Jamie Josephine Avila, Ndaw, Victor, Abebayehu, Daniel, Barnstein, Brian O., Faber, Travis, Spence, Andrew J., Taruselli, Marcela, Paranjape, Anuya, Haque, Tamara T., Qayum, Amina Abdul, Wijesinghe, Dayanjan S., Sturgill, Jamie L., Chalfant, Charles E., Straus, David B., Oskeritzian, Carole A., Ryan, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744515/
https://ncbi.nlm.nih.gov/pubmed/26773154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501932
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