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Fluvastatin Suppresses Mast Cell and Basophil IgE Responses: Genotype-Dependent Effects

Mast cell- and basophil-associated inflammatory diseases are a considerable burden to society. A significant portion of patients have symptoms despite standard-of-care therapy. Statins, used to lower serum cholesterol, have immune modulating activities. We tested the in vitro and in vivo effects of...

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Библиографические подробности
Опубликовано в: :J Immunol
Главные авторы: Kolawole, Elizabeth Motunrayo, McLeod, Jamie Josephine Avila, Ndaw, Victor, Abebayehu, Daniel, Barnstein, Brian O., Faber, Travis, Spence, Andrew J., Taruselli, Marcela, Paranjape, Anuya, Haque, Tamara T., Qayum, Amina Abdul, Wijesinghe, Dayanjan S., Sturgill, Jamie L., Chalfant, Charles E., Straus, David B., Oskeritzian, Carole A., Ryan, John J.
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744515/
https://ncbi.nlm.nih.gov/pubmed/26773154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501932
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