Fluvastatin Suppresses Mast Cell and Basophil IgE Responses: Genotype-Dependent Effects

Mast cell- and basophil-associated inflammatory diseases are a considerable burden to society. A significant portion of patients have symptoms despite standard-of-care therapy. Statins, used to lower serum cholesterol, have immune modulating activities. We tested the in vitro and in vivo effects of...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Immunol
Prif Awduron: Kolawole, Elizabeth Motunrayo, McLeod, Jamie Josephine Avila, Ndaw, Victor, Abebayehu, Daniel, Barnstein, Brian O., Faber, Travis, Spence, Andrew J., Taruselli, Marcela, Paranjape, Anuya, Haque, Tamara T., Qayum, Amina Abdul, Wijesinghe, Dayanjan S., Sturgill, Jamie L., Chalfant, Charles E., Straus, David B., Oskeritzian, Carole A., Ryan, John J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744515/
https://ncbi.nlm.nih.gov/pubmed/26773154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501932
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