Didox (3,4-dihydroxybenzohydroxamic acid) suppresses IL-33-induced cytokine production in primary mouse mast cells

While IgE is considered the primary mediator of mast cell activation, IL-33 contributes substantially in asthma, allergic rhinitis, and atopic dermatitis. To develop effective treatments for allergic disease, it is important to understand the role of therapeutic agents on IL-33 activation. We examin...

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Veröffentlicht in:Cell Immunol
Hauptverfasser: Caslin, Heather L., McLeod, Jamie Josephine Avila, Spence, Andrew J., Qayum, Amina Abdul, Kolawole, Elizabeth Motunrayo, Taruselli, Marcela T., Paranjape, Anuya, Elford, Howard L., Ryan, John J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593780/
https://ncbi.nlm.nih.gov/pubmed/28750923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2017.04.013
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