Fluvastatin Suppresses Mast Cell and Basophil IgE Responses: Genotype-Dependent Effects

Mast cell- and basophil-associated inflammatory diseases are a considerable burden to society. A significant portion of patients have symptoms despite standard-of-care therapy. Statins, used to lower serum cholesterol, have immune modulating activities. We tested the in vitro and in vivo effects of...

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Vydáno v:J Immunol
Hlavní autoři: Kolawole, Elizabeth Motunrayo, McLeod, Jamie Josephine Avila, Ndaw, Victor, Abebayehu, Daniel, Barnstein, Brian O., Faber, Travis, Spence, Andrew J., Taruselli, Marcela, Paranjape, Anuya, Haque, Tamara T., Qayum, Amina Abdul, Wijesinghe, Dayanjan S., Sturgill, Jamie L., Chalfant, Charles E., Straus, David B., Oskeritzian, Carole A., Ryan, John J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744515/
https://ncbi.nlm.nih.gov/pubmed/26773154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501932
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