Lactic acid suppresses IgE-mediated mast cell function in vitro and in vivo

Mast cells have functional plasticity affected by their tissue microenvironment, which greatly impacts their inflammatory responses. Because lactic acid (LA) is abundant in inflamed tissues and tumors, we investigated how it affects mast cell function. Using IgE-mediated activation as a model system...

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Detalhes bibliográficos
Publicado no:Cell Immunol
Main Authors: Abebayehu, Daniel, Spence, Andrew J., Caslin, Heather, Taruselli, Marcela, Haque, Tamara T., Kiwanuka, Kasalina N., Kolawole, Elizabeth Motunrayo, Chumanevich, Alena P., Sell, Scott A., Oskeritzian, Carole A., Ryan, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579658/
https://ncbi.nlm.nih.gov/pubmed/31030957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2019.04.006
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