Lactic acid suppresses IgE-mediated mast cell function in vitro and in vivo

Mast cells have functional plasticity affected by their tissue microenvironment, which greatly impacts their inflammatory responses. Because lactic acid (LA) is abundant in inflamed tissues and tumors, we investigated how it affects mast cell function. Using IgE-mediated activation as a model system...

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Foilsithe in:Cell Immunol
Main Authors: Abebayehu, Daniel, Spence, Andrew J., Caslin, Heather, Taruselli, Marcela, Haque, Tamara T., Kiwanuka, Kasalina N., Kolawole, Elizabeth Motunrayo, Chumanevich, Alena P., Sell, Scott A., Oskeritzian, Carole A., Ryan, John
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2019
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579658/
https://ncbi.nlm.nih.gov/pubmed/31030957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2019.04.006
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