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Lactic acid suppresses IgE-mediated mast cell function in vitro and in vivo

Mast cells have functional plasticity affected by their tissue microenvironment, which greatly impacts their inflammatory responses. Because lactic acid (LA) is abundant in inflamed tissues and tumors, we investigated how it affects mast cell function. Using IgE-mediated activation as a model system...

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Bibliografiske detaljer
Udgivet i:Cell Immunol
Main Authors: Abebayehu, Daniel, Spence, Andrew J., Caslin, Heather, Taruselli, Marcela, Haque, Tamara T., Kiwanuka, Kasalina N., Kolawole, Elizabeth Motunrayo, Chumanevich, Alena P., Sell, Scott A., Oskeritzian, Carole A., Ryan, John
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579658/
https://ncbi.nlm.nih.gov/pubmed/31030957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2019.04.006
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