Fluvastatin Induces Apoptosis in Primary and Transformed Mast Cells

Statin drugs are widely employed in the clinic to reduce serum cholesterol. Because of their hydroxymethylglutaryl coenzyme A reductase antagonism, statins also reduce isoprenyl lipids necessary for the membrane anchorage and signaling of small G-proteins in the Ras superfamily. We previously found...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Pharmacol Exp Ther
Egile Nagusiak: Paez, Patrick A., Kolawole, Motunrayo, Taruselli, Marcela T., Ajith, Siddarth, Dailey, Jordan M., Kee, Sydney A., Haque, Tamara T., Barnstein, Brian O., McLeod, Jamie Josephine Avila, Caslin, Heather L., Kiwanuka, Kasalina N., Fukuoka, Yoshihiro, Le, Quang T., Schwartz, Lawrence B., Straus, David B., Gewirtz, David A., Martin, Rebecca K., Ryan, John J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Pharmacology and Experimental Therapeutics 2020
Gaiak:
Inflammation, Immunopharmacology, and Asthma
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7306917/
https://ncbi.nlm.nih.gov/pubmed/32434944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.119.264234
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