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Fluvastatin Induces Apoptosis in Primary and Transformed Mast Cells
Statin drugs are widely employed in the clinic to reduce serum cholesterol. Because of their hydroxymethylglutaryl coenzyme A reductase antagonism, statins also reduce isoprenyl lipids necessary for the membrane anchorage and signaling of small G-proteins in the Ras superfamily. We previously found...
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| Publicado no: | J Pharmacol Exp Ther |
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| Main Authors: | , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7306917/ https://ncbi.nlm.nih.gov/pubmed/32434944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.119.264234 |
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