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Hydrogen Atom Abstraction by High-Valent Fe(OH) versus Mn(OH) Porphyrinoid Complexes: Mechanistic Insights from Experimental and Computational Studies

High-valent metal-hydroxide species have been implicated as key intermediates in hydroxylation chemistry catalyzed by heme monooxygenases such as the cytochrome P450s. However, in some classes of P450s, a bifurcation from the typical oxygen rebound pathway is observed, wherein the protonated Fe(rV)(...

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發表在:Inorg Chem
Main Authors: Zaragoza, Jan Paulo T., Cummins, Daniel C., Mubarak, M. Qadri E., Siegler, Maxime A., de Visser, Sam P., Goldberg, David P.
格式: Artigo
語言:Inglês
出版: 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7271964/
https://ncbi.nlm.nih.gov/pubmed/31804814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.inorgchem.9b02923
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