BSCI-11. STROMAL PLATELET DERIVED GROWTH FACTOR RECEPTOR-β (PDGFRβ) PROMOTES BREAST CANCER BRAIN METASTASIS

Stromal platelet-derived growth factor receptor-beta (PDGFRβ) has emerged as an actionable mediator of breast tumor-stromal communication. As a receptor tyrosine kinase, PDGFRβ is activated by its ligand, PDGFB, which is released by neighboring tumor epithelium and endothelium. However, how PDGF sig...

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Veröffentlicht in:Neurooncol Adv
Hauptverfasser: Thies, Katie, Hammer, Anisha, Hildreth, Blake, Russell, Luke, Sizemore, Steven, Trimboli, Anthony, Kladney, Raleigh, Steck, Sarah, Das, Manjusri, Bolyard, Chelsea, Pilarski, Robert, Cuitino, Maria, Koivisto, Christopher, Schoenfield, Lynn, Otero, Jose, Chakravarti, Arnab, Ringel, Matthew, Li, Zaibo, Kaur, Balveen, Leone, Gustavo, Ostrowski, Michael, Sizemore, Gina
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
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Abstracts
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7213233/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdz014.009
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