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Stromal PTEN determines mammary epithelial response to radiotherapy

The importance of the tumor–associated stroma in cancer progression is clear. However, it remains uncertain whether early events in the stroma are capable of initiating breast tumorigenesis. Here, we show that in the mammary glands of non-tumor bearing mice, stromal-specific phosphatase and tensin h...

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Bibliografski detalji
Izdano u:Nat Commun
Glavni autori: Sizemore, Gina M., Balakrishnan, Subhasree, Thies, Katie A., Hammer, Anisha M., Sizemore, Steven T., Trimboli, Anthony J., Cuitiño, Maria C., Steck, Sarah A., Tozbikian, Gary, Kladney, Raleigh D., Shinde, Neelam, Das, Manjusri, Park, Dongju, Majumder, Sarmila, Krishnan, Shiva, Yu, Lianbo, Fernandez, Soledad A., Chakravarti, Arnab, Shields, Peter G., White, Julia R., Yee, Lisa D., Rosol, Thomas J., Ludwig, Thomas, Park, Morag, Leone, Gustavo, Ostrowski, Michael C.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050339/
https://ncbi.nlm.nih.gov/pubmed/30018330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05266-6
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