Stromal PTEN determines mammary epithelial response to radiotherapy

The importance of the tumor–associated stroma in cancer progression is clear. However, it remains uncertain whether early events in the stroma are capable of initiating breast tumorigenesis. Here, we show that in the mammary glands of non-tumor bearing mice, stromal-specific phosphatase and tensin h...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Sizemore, Gina M., Balakrishnan, Subhasree, Thies, Katie A., Hammer, Anisha M., Sizemore, Steven T., Trimboli, Anthony J., Cuitiño, Maria C., Steck, Sarah A., Tozbikian, Gary, Kladney, Raleigh D., Shinde, Neelam, Das, Manjusri, Park, Dongju, Majumder, Sarmila, Krishnan, Shiva, Yu, Lianbo, Fernandez, Soledad A., Chakravarti, Arnab, Shields, Peter G., White, Julia R., Yee, Lisa D., Rosol, Thomas J., Ludwig, Thomas, Park, Morag, Leone, Gustavo, Ostrowski, Michael C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050339/
https://ncbi.nlm.nih.gov/pubmed/30018330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05266-6
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