Stromal PTEN determines mammary epithelial response to radiotherapy

The importance of the tumor–associated stroma in cancer progression is clear. However, it remains uncertain whether early events in the stroma are capable of initiating breast tumorigenesis. Here, we show that in the mammary glands of non-tumor bearing mice, stromal-specific phosphatase and tensin h...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Nat Commun
Autori principali: Sizemore, Gina M., Balakrishnan, Subhasree, Thies, Katie A., Hammer, Anisha M., Sizemore, Steven T., Trimboli, Anthony J., Cuitiño, Maria C., Steck, Sarah A., Tozbikian, Gary, Kladney, Raleigh D., Shinde, Neelam, Das, Manjusri, Park, Dongju, Majumder, Sarmila, Krishnan, Shiva, Yu, Lianbo, Fernandez, Soledad A., Chakravarti, Arnab, Shields, Peter G., White, Julia R., Yee, Lisa D., Rosol, Thomas J., Ludwig, Thomas, Park, Morag, Leone, Gustavo, Ostrowski, Michael C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050339/
https://ncbi.nlm.nih.gov/pubmed/30018330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05266-6
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi