Stromal PTEN inhibits the expansion of mammary epithelial stem cells through Jagged-1

Fibroblasts within the mammary tumor microenvironment are active participants in carcinogenesis mediating both tumor initiation and progression. Our group has previously demonstrated that genetic loss of PTEN in mammary fibroblasts induces an oncogenic secretome that remodels the extracellular milie...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncogene
Prif Awduron: Sizemore, GM, Balakrishnan, S, Hammer, AM, Thies, KA, Trimboli, AJ, Wallace, JA, Sizemore, ST, Kladney, RD, Woelke, SA, Yu, L, Fernandez, SA, Chakravarti, A, Leone, G, Ostrowski, MC
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5398932/
https://ncbi.nlm.nih.gov/pubmed/27797378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.383
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