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Exploring the prime site in caspases as a novel chemical strategy for understanding the mechanisms of cell death: a proof of concept study on necroptosis in cancer cells

Caspases participate in regulated cell death mechanisms and are divided into apoptotic and proinflammatory caspases. The main problem in identifying the unique role of a particular caspase in the mechanisms of regulated cell death is their overlapping substrate specificity; caspases recognize and hy...

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Detalles Bibliográficos
Publicado en:Cell Death Differ
Main Authors: Groborz, Katarzyna, Gonzalez Ramirez, Monica L., Snipas, Scott J., Salvesen, Guy S., Drąg, Marcin, Poręba, Marcin
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205877/
https://ncbi.nlm.nih.gov/pubmed/31209360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0364-z
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