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Exploring the prime site in caspases as a novel chemical strategy for understanding the mechanisms of cell death: a proof of concept study on necroptosis in cancer cells

Caspases participate in regulated cell death mechanisms and are divided into apoptotic and proinflammatory caspases. The main problem in identifying the unique role of a particular caspase in the mechanisms of regulated cell death is their overlapping substrate specificity; caspases recognize and hy...

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Bibliographic Details
Published in:Cell Death Differ
Main Authors: Groborz, Katarzyna, Gonzalez Ramirez, Monica L., Snipas, Scott J., Salvesen, Guy S., Drąg, Marcin, Poręba, Marcin
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205877/
https://ncbi.nlm.nih.gov/pubmed/31209360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0364-z
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