Structure—Activity Relationship of Antischistosomal Ozonide Carboxylic Acids

Semisynthetic artemisinins and other bioactive peroxides are best known for their powerful antimalarial activities, and they also show substantial activity against schistosomes—another hemoglobin-degrading pathogen. Building on this discovery, we now describe the initial structure—activity relations...

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Detalhes bibliográficos
Publicado no:J Med Chem
Main Authors: Wu, Jianbo, Wang, Xiaofang, Chiu, Francis C. K., Häberli, Ćecile, Shackleford, David M., Ryan, Eileen, Kamaraj, Sriraghavan, Bulbule, Vivek J., Wallick, Alexander I., Dong, Yuxiang, White, Karen L., Davis, Paul H., Charman, Susan A., Keiser, Jennifer, Vennerstrom, Jonathan L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7182039/
https://ncbi.nlm.nih.gov/pubmed/32134263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.0c00069
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