Structure—Activity Relationship of Antischistosomal Ozonide Carboxylic Acids

Semisynthetic artemisinins and other bioactive peroxides are best known for their powerful antimalarial activities, and they also show substantial activity against schistosomes—another hemoglobin-degrading pathogen. Building on this discovery, we now describe the initial structure—activity relations...

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Publicado en:J Med Chem
Autores principales: Wu, Jianbo, Wang, Xiaofang, Chiu, Francis C. K., Häberli, Ćecile, Shackleford, David M., Ryan, Eileen, Kamaraj, Sriraghavan, Bulbule, Vivek J., Wallick, Alexander I., Dong, Yuxiang, White, Karen L., Davis, Paul H., Charman, Susan A., Keiser, Jennifer, Vennerstrom, Jonathan L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7182039/
https://ncbi.nlm.nih.gov/pubmed/32134263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.0c00069
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