In Vivo Activity of Aryl Ozonides against Schistosoma Species

We evaluated the in vivo antischistosomal activities of 11 structurally diverse synthetic peroxides. Of all compounds tested, ozonide (1,2,4-trioxolane) OZ418 had the highest activity against adult Schistosoma mansoni, with total and female worm burden reductions of 80 and 90% (P < 0.05), respect...

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Detaylı Bibliyografya
Asıl Yazarlar: Keiser, Jennifer, Ingram, Katrin, Vargas, Mireille, Chollet, Jacques, Wang, Xiaofang, Dong, Yuxiang, Vennerstrom, Jonathan L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2012
Konular:
Experimental Therapeutics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264258/
https://ncbi.nlm.nih.gov/pubmed/22106214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05371-11
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