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Antimicrobials Inspired by Nonribosomal Peptide Synthetase Gene Clusters
Bacterial culture broth extracts have been the starting point for the development of numerous therapeutics. However, only a small fraction of bacterial biosynthetic diversity is accessible using this strategy. Here, we apply a discovery approach that bypasses the culturing step entirely by bioinform...
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| Опубликовано в: : | J Am Chem Soc |
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| Главные авторы: | , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7163397/ https://ncbi.nlm.nih.gov/pubmed/28055186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b11861 |
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