Malleilactone, a polyketide synthase-derived virulence factor encoded by the cryptic secondary metabolome of Burkholderia pseudomallei group pathogens

Por Biggins, John B., Ternei, Melinda A., Brady, Sean F.
Publicado em 2012

Discovery and synthetic refactoring of tryptophan dimer gene clusters from the environment

Por Chang, Fang-Yuan, Ternei, Melinda A., Calle, Paula Y., Brady, Sean F.
Publicado em 2013

Targeted metagenomics: finding rare tryptophan dimer natural products in the environment

Por Chang, Fang-Yuan, Ternei, Melinda A., Calle, Paula Y., Brady, Sean F.
Publicado no J Am Chem Soc (2015)

The Chemical Arsenal of Burkholderia pseudomallei Is Essential for Pathogenicity

Por Biggins, John B., Kang, Hahk-Soo, Ternei, Melinda A., DeShazer, David, Brady, Sean F.
Publicado em 2014

Chemical-biogeographic survey of secondary metabolism in soil

Por Charlop-Powers, Zachary, Owen, Jeremy G., Reddy, Boojala Vijay B., Ternei, Melinda A., Brady, Sean F.
Publicado em 2014

Mapping gene clusters within arrayed metagenomic libraries to expand the structural diversity of biomedically relevant natural products

Por Owen, Jeremy G., Reddy, Boojala Vijay B., Ternei, Melinda A., Charlop-Powers, Zachary, Calle, Paula Y., Kim, Jeffrey H., Brady, Sean F.
Publicado em 2013

Multiplexed metagenome mining using short DNA sequence tags facilitates targeted discovery of epoxyketone proteasome inhibitors

Por Owen, Jeremy G., Charlop-Powers, Zachary, Smith, Alexandra G., Ternei, Melinda A., Calle, Paula Y., Reddy, Boojala Vijay B., Montiel, Daniel, Brady, Sean F.
Publicado no Proc Natl Acad Sci U S A (2015)

Functional metagenomic discovery of bacterial effectors in the human microbiome and isolation of commendamide, a GPCR G2A/132 agonist

Por Cohen, Louis J., Kang, Hahk-Soo, Chu, John, Huang, Yun-Han, Gordon, Emma A., Reddy, Boojala Vijay B., Ternei, Melinda A., Craig, Jeffrey W., Brady, Sean F.
Publicado no Proc Natl Acad Sci U S A (2015)

Global biogeographic sampling of bacterial secondary metabolism

Por Charlop-Powers, Zachary, Owen, Jeremy G, Reddy, Boojala Vijay B, Ternei, Melinda A, Guimarães, Denise O, de Frias, Ulysses A, Pupo, Monica T, Seepe, Prudy, Feng, Zhiyang, Brady, Sean F
Publicado no eLife (2015)

Urban park soil microbiomes are a rich reservoir of natural product biosynthetic diversity

Por Charlop-Powers, Zachary, Pregitzer, Clara C., Lemetre, Christophe, Ternei, Melinda A., Maniko, Jeffrey, Hover, Bradley M., Calle, Paula Y., McGuire, Krista L., Garbarino, Jeanne, Forgione, Helen M., Charlop-Powers, Sarah, Brady, Sean F.
Publicado no Proc Natl Acad Sci U S A (2016)