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Discovery and synthetic refactoring of tryptophan dimer gene clusters from the environment
Here we investigate bacterial tryptophan dimer (TD) biosynthesis by probing environmental DNA (eDNA) libraries for chromopyrrolic acid (CPA) synthase genes. Functional and bioinformatics analyses of TD clusters indicate that CPA synthase gene sequences diverge in concert with the functional output o...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3878720/ https://ncbi.nlm.nih.gov/pubmed/24171465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja408683p |
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