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Malleilactone, a polyketide synthase-derived virulence factor encoded by the cryptic secondary metabolome of Burkholderia pseudomallei group pathogens

Sequenced bacterial genomes are routinely found to contain gene clusters that are predicted to encode metabolites not seen in fermentation based studies. Pseudomallei group Burkholderia are emerging pathogens whose genomes are particularly rich in cryptic natural product biosynthetic gene clusters....

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Detalhes bibliográficos
Main Authors: Biggins, John B., Ternei, Melinda A., Brady, Sean F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3514402/
https://ncbi.nlm.nih.gov/pubmed/22765305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3052156
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