Malleilactone Is a Burkholderia pseudomallei Virulence Factor Regulated by Antibiotics and Quorum Sensing

Burkholderia pseudomallei, the causative agent of melioidosis, encodes almost a dozen predicted polyketide (PK) biosynthetic gene clusters. Many of these are regulated by LuxR-I-type acyl-homoserine (AHL) quorum-sensing systems. One of the PK gene clusters, the mal gene cluster, is conserved in the...

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Vydáno v:J Bacteriol
Hlavní autoři: Klaus, Jennifer R., Deay, Jacqueline, Neuenswander, Benjamin, Hursh, Wyatt, Gao, Zhe, Bouddhara, Tiffany, Williams, Todd D., Douglas, Justin, Monize, Kyle, Martins, Patricia, Majerczyk, Charlotte, Seyedsayamdost, Mohammad R., Peterson, Blake R., Rivera, Mario, Chandler, Josephine R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2018
Témata:
Meeting Presentation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6018353/
https://ncbi.nlm.nih.gov/pubmed/29735757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00008-18
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