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Functional metagenomic discovery of bacterial effectors in the human microbiome and isolation of commendamide, a GPCR G2A/132 agonist

The trillions of bacteria that make up the human microbiome are believed to encode functions that are important to human health; however, little is known about the specific effectors that commensal bacteria use to interact with the human host. Functional metagenomics provides a systematic means of s...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Cohen, Louis J., Kang, Hahk-Soo, Chu, John, Huang, Yun-Han, Gordon, Emma A., Reddy, Boojala Vijay B., Ternei, Melinda A., Craig, Jeffrey W., Brady, Sean F.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568208/
https://ncbi.nlm.nih.gov/pubmed/26283367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1508737112
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