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Identification of biosynthetic gene clusters from metagenomic libraries using PPTase complementation in a Streptomyces host
The majority of environmental bacteria are not readily cultured in the lab, leaving the natural products they make inaccessible using culture-dependent discovery methods. Cloning and heterologous expression of DNA extracted from environmental samples (environmental DNA, eDNA) provides a means of cir...
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| Publicat a: | FEMS Microbiol Lett |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5827622/ https://ncbi.nlm.nih.gov/pubmed/28817927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/femsle/fnx155 |
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