Oncogenic ERG represses PI3K signaling through down-regulation of IRS2

Genomic rearrangements leading to the aberrant expression of ERG are the most common early events in prostate cancer and are significantly enriched for the concomitant loss of PTEN. Genetically engineered mouse models reveal that ERG overexpression alone is not sufficient to induce tumorigenesis, bu...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cancer Res
Main Authors: Mao, Ninghui, Gao, Dong, Hu, Wenhuo, Gadal, Sunyana, Hieronymus, Haley, Wang, Shangqian, Lee, Young Sun, Sullivan, Patrick, Zhang, Zeda, Choi, Danielle, Rosen, Neal, Sawyers, Charles L, Gopalan, Anuradha, Chen, Yu, Carver, Brett S
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7127960/
https://ncbi.nlm.nih.gov/pubmed/32015092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-1394
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker