Oncogenic ERG represses PI3K signaling through down-regulation of IRS2

Genomic rearrangements leading to the aberrant expression of ERG are the most common early events in prostate cancer and are significantly enriched for the concomitant loss of PTEN. Genetically engineered mouse models reveal that ERG overexpression alone is not sufficient to induce tumorigenesis, bu...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Res
Egile Nagusiak: Mao, Ninghui, Gao, Dong, Hu, Wenhuo, Gadal, Sunyana, Hieronymus, Haley, Wang, Shangqian, Lee, Young Sun, Sullivan, Patrick, Zhang, Zeda, Choi, Danielle, Rosen, Neal, Sawyers, Charles L, Gopalan, Anuradha, Chen, Yu, Carver, Brett S
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7127960/
https://ncbi.nlm.nih.gov/pubmed/32015092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-1394
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