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Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis
The TMPRSS2-ERG fusion, present in 50% of prostate cancers, is less common in prostatic intra-epithelial neoplasia (PIN), raising questions about whether TMPRSS2-ERG contributes to disease initiation. We identified the translational start site of a common TMPRSS2-ERG fusion and showed that transgeni...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2898503/ https://ncbi.nlm.nih.gov/pubmed/19396167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.371 |
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