MYC Cooperates with AKT in Prostate Tumorigenesis and Alters Sensitivity to mTOR Inhibitors

MYC and phosphoinositide 3-kinase (PI3K)-pathway deregulation are common in human prostate cancer. Through examination of 194 human prostate tumors, we observed statistically significant co-occurrence of MYC amplification and PI3K-pathway alteration, raising the possibility that these two lesions co...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Clegg, Nicola J., Couto, Suzana S., Wongvipat, John, Hieronymus, Haley, Carver, Brett S., Taylor, Barry S., Ellwood-Yen, Katharine, Gerald, William L., Sander, Chris, Sawyers, Charles L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2011
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048873/
https://ncbi.nlm.nih.gov/pubmed/21394210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017449
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller