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The role of the Akt/mTOR pathway in tobacco-carcinogen induced lung tumorigenesis

Lung cancer is the leading cause of cancer-related death in the United States, and 85–90% of lung cancer cases are associated with tobacco use. Tobacco components promote lung tumorigenesis through genotoxic effects, as well as through biochemical modulation of signaling pathways such as the Akt/mTO...

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Detalhes bibliográficos
Main Authors: Memmott, Regan M., Dennis, Phillip A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805044/
https://ncbi.nlm.nih.gov/pubmed/20028747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-0234
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