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Akt-dependent and independent mechanisms of mTOR regulation in cancer
The protein kinase mTOR (mammalian target of rapamycin) is a critical regulator of cellular metabolism, growth, and proliferation. These processes contribute to tumor formation, and many cancers are characterized by aberrant activation of mTOR. Although activating mutations in mTOR itself have not b...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2650010/ https://ncbi.nlm.nih.gov/pubmed/19166931 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2009.01.004 |
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