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Metformin prevents tobacco carcinogen-induced lung tumorigenesis

Activation of the mTOR pathway is an important and early event in tobacco carcinogen-induced lung tumorigenesis, and therapies that target mTOR could be effective in the prevention or treatment of lung cancer. The biguanide metformin, which is widely prescribed for the treatment of type II diabetes,...

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Main Authors: Memmott, Regan M., Mercado, Jose R., Maier, Colleen R., Kawabata, Shigeru, Fox, Stephen D., Dennis, Phillip A.
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192328/
https://ncbi.nlm.nih.gov/pubmed/20810672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-10-0055
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