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Metformin prevents tobacco carcinogen-induced lung tumorigenesis

Activation of the mTOR pathway is an important and early event in tobacco carcinogen-induced lung tumorigenesis, and therapies that target mTOR could be effective in the prevention or treatment of lung cancer. The biguanide metformin, which is widely prescribed for the treatment of type II diabetes,...

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Detalhes bibliográficos
Main Authors: Memmott, Regan M., Mercado, Jose R., Maier, Colleen R., Kawabata, Shigeru, Fox, Stephen D., Dennis, Phillip A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192328/
https://ncbi.nlm.nih.gov/pubmed/20810672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-10-0055
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